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Updated: Feb 8, 2026
05:26
Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
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Discharge timing and outcomes after uncomplicated non-ST-segment elevation acute myocardial infarction
Jennifer A Rymer1, Michael W Tempelhof2, Robert M Clare3
1Department of Medicine, Duke University Medical Center, Durham, NC.
American Heart Journal
|June 19, 2018
Summary
Patients hospitalized for non-ST-segment elevation myocardial infarction (NSTEMI) with no early complications have low risk for later cardiac events. Early discharge for these NSTEMI patients is safe and associated with favorable survival outcomes.
Area of Science:
- Cardiology
- Clinical Medicine
- Health Services Research
Background:
- Hospital length of stay for non-ST-segment elevation myocardial infarction (NSTEMI) is decreasing.
- Limited data exists to guide optimal NSTEMI hospitalization duration.
Purpose of the Study:
- To estimate complication rates and event-free survival after discharge for NSTEMI patients.
- To assess the association between discharge timing and patient outcomes.
Main Methods:
- Landmark analyses were used to define potential discharge days.
- Complication rates were estimated on potential discharge days.
- Associations between discharge timing and 30-day/1-year event-free survival were analyzed in 20,410 NSTEMI patients.
Main Results:
- 15.7% of NSTEMI patients had cardiac complications within the first 2 days.
- 10.6% discharged on day 3 without complications had 99.1% 30-day event-free survival.
- 1,706 patients discharged on day 4 without complications had 98.0% 30-day event-free survival.
Conclusions:
- NSTEMI patients without complications in the first 2 days are at low risk for subsequent adverse events.
- Early discharge for select NSTEMI patients is associated with favorable short- and intermediate-term survival.
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