Related Experiment Video
Updated: Feb 8, 2026

Pancreatic Duct Infusion: An Effective and Selective Method of Drug and Viral Delivery
Published on: September 30, 2021
Detection of traumatic pancreatic duct disruption in the modern era
Morgan Schellenberg1, Kenji Inaba1, James M Bardes1
1Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, CA, 2051 Marengo Street, IPT C5L100, Los Angeles, CA 90033, United States.
Background:
Pancreatic trauma management hinges upon the presence or absence of pancreatic duct injury, but the optimal method of assessment is unclear. This study endeavored to evaluate the methods of pancreatic duct assessment in modern practice.
Methods:
Patients presenting to LAC + USC Medical Center (01/2008-06/2015) with a pancreatic injury were identified (ICD-9 codes). Demographics, clinical data, technique of duct evaluation, and outcomes were analyzed.
Results:
71 patients with pancreatic injury were identified. 21 patients (30%) underwent CT scan (sensitivity 76%). Sixteen (76%) then underwent laparotomy while 5 (24%) were managed successfully nonoperatively. Most (n = 50, 70%) underwent immediate laparotomy. Overall, 66 patients (93%) were managed operatively. The majority were assessed intraoperatively for ductal injury with visual inspection alone (n = 62, 94%). Four (6%) underwent intraoperative pancreatography via duodenotomy/cholecystotomy, which were all inconclusive.
Conclusion:
In the evaluation of pancreatic duct injury, intraoperative pancreatography is frequently inconclusive and should have a limited role. Clinical suspicion for ductal injury based on intraoperative visual inspection alone should guide the management of pancreatic injuries.
More Related Videos
Related Concept Videos
Modern Molecular Taxonomy
Traumatic Memory
Alveoli and Alveolar Ducts
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Accessory Ducts of the Male Reproductive System
The epididymis is a small, comma-shaped organ located at the back of each testicle....
Reabsorption and Secretion in the DCT and Collecting Duct
The distal...

