Related Experiment Video
Updated: Feb 8, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Wide volume versus helical acquisition using 320-detector row computed tomography for computed tomography urography
1Department of Radiology B, University Hospital of Strasbourg-Hôpital Civil 1, place de l'hôpital, 67091 Strasbourg cedex, France.
Purpose:
To evaluate the best collimation used in wide volume (WV) mode to cover the abdomen in computed tomography (CT) urography in terms of radiation dose and image quality.
Materials And Methods:
This study was performed on a 320×0.5mm detector row CT unit. The first part identified the lowest volume CT dose index (CTDIvol) by using the topograms data of 25 medium size patients (13 men and 12 women; mean age: 52±9 [SD] years; age range: 46-68 years) using different collimations on WV from 6cm to 16cm and the one of the helical mode for the same coverage length. The second part consisted of a clinical evaluation of this result including 45 medium size patients (32 men and 13 women; mean age: 68±14 [SD] years; age range: 45-72 years). The qualitative evaluation included several items based on a 5-point Likert scale.
Results:
The first part of the study indicated that a collimation of 10cm (200×0.5mm) in WV mode with 5 volumes had the lowest CTDIvol (2.78±0.35mGy; range: 2.35-3.21mGy) compared to helical mode (4.38±0.48mGy, range: 3.75-4.95mGy). In the second part, the mean radiation dose reduction by comparison with helical mode was 44.03%±0.36% (P<0.001) and 51.16%±1.22% (P<0.005) for CTDIvol and DLP, respectively.
Conclusion:
Wide volume mode of the abdomen can be performed with a significant radiation dose reduction with a collimation of 10cm (200×0.5mm) and five volumes.
Related Concept Videos
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography
Design Example: Traverse Angle Computations
Area Computation by the Alternative Coordinate Method
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
The Role of Ion Channels in Neuronal Computation
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential....

