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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

1.8K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Pancreatic Juice and Secretion01:26

Pancreatic Juice and Secretion

3.1K
Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
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Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Robotic Lateral Pancreaticojejunostomy for Chronic Pancreatitis
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Autoimmune Pancreatitis.

Sajan Jiv Singh Nagpal1, Ayush Sharma1, Suresh T Chari1

  • 1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

The American Journal of Gastroenterology
|June 19, 2018
PubMed
Summary
This summary is machine-generated.

Autoimmune pancreatitis (AIP) is a rare condition causing painless jaundice and recurrent pancreatitis. Steroids are primary treatment, but some patients need additional therapies like immunomodulators for remission.

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Area of Science:

  • Gastroenterology
  • Immunology
  • Pancreatology

Background:

  • Autoimmune pancreatitis (AIP) knowledge has grown significantly over the past 20 years.
  • AIP is a rare but crucial differential diagnosis for painless obstructive jaundice and recurrent acute pancreatitis.

Purpose of the Study:

  • To review the clinical presentation, diagnosis, and treatment of AIP.
  • To aid gastroenterologists and primary care providers in recognizing and managing AIP.

Main Methods:

  • Literature review of autoimmune pancreatitis.
  • Synthesis of current clinical guidelines and research findings.

Main Results:

  • Steroids are the primary treatment for AIP.
  • Some patients with type 1 AIP require immunomodulators or rituximab for sustained remission.
  • Management strategies for AIP relapses are continually evolving.

Conclusions:

  • Enhanced understanding of AIP aids clinical practice.
  • Multifaceted treatment approaches are necessary for AIP management.
  • Ongoing research is vital for refining AIP treatment protocols.