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Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
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Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients

Published on: September 20, 2020

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The Impact of Transarterial Chemoembolization for Advanced Stage Hepatocellular Carcinoma: A Single Center Experience

Nisit Tongsiri, Somboon Subwongcharoen, Sa-ard Treepongkaruna

    Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
    |June 19, 2018
    PubMed

    Insights

    Transarterial chemoembolization (TACE) is a safe and effective palliative treatment for hepatocellular carcinoma (HCC) patients in Barcelona Clinic Liver Cancer (BCLC) stage C. This study evaluated survival and complications in HCC patients receiving TACE.

    Area of Science:

    • Hepatology
    • Oncology
    • Interventional Radiology

    Background:

    • Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide.
    • Barcelona Clinic Liver Cancer (BCLC) staging system is crucial for guiding treatment decisions.
    • Transarterial chemoembolization (TACE) is a common palliative treatment for intermediate-stage HCC.

    Purpose of the Study:

    • To evaluate the survival outcomes and complications of hepatocellular carcinoma (HCC) patients.
    • To assess the efficacy and safety of transarterial chemoembolization (TACE) in BCLC stage C HCC patients.
    • To analyze data from Rajavithi Hospital, Thailand, between 2008 and 2012.

    Main Methods:

    • A descriptive retrospective study design was employed.
    • Data were collected from patient medical records.
    • Survival analysis was performed using the Kaplan-Meier method.

    Main Results:

    • The study included 44 patients with BCLC stage C HCC who received TACE.
    • Median survival time was 7.1 months.
    • Post-embolization syndrome (88.6%) was the most common complication, while liver failure (18.2%) was a major procedural-related complication.

    Conclusions:

    • Transarterial chemoembolization (TACE) demonstrated effectiveness and safety as a palliative treatment for HCC patients with BCLC stage C.
    • The findings support the use of TACE in managing advanced HCC.
    • Further research can explore optimizing TACE protocols for improved patient outcomes.
    Abstract

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