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Economic burden of patients with diffuse large B-cell and follicular lymphoma treated in the USA

Vicki A Morrison1, Jill A Bell2, Laurie Hamilton3

  • 1Hematology/Oncology & Infectious Disease, Hennepin County Medical Center, University of Minnesota, 701 Park Ave Ste 310, Minneapolis, MN 55415, USA.

Future Oncology (London, England)
|June 19, 2018
PubMed

Insights

The economic burden of treating diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) is significant, particularly in the initial year post-diagnosis. Costs and healthcare utilization decrease in the second year.

Area of Science:

  • Hematology
  • Oncology
  • Health Economics

Background:

  • Diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) are common B-cell malignancies.
  • Understanding the economic impact of these diseases is crucial for healthcare planning and resource allocation.

Purpose of the Study:

  • To evaluate the healthcare costs and utilization patterns associated with treated DLBCL and FL patients.
  • To assess the economic burden in the initial period following diagnosis.

Main Methods:

  • Retrospective analysis of adult patients with newly diagnosed DLBCL and FL.
  • Data sourced from the Optum™ claims database between January 1, 2008, and October 31, 2015.
  • Healthcare costs and utilization were tracked from diagnosis to the end of the follow-up period.

Main Results:

  • The study identified 1267 DLBCL and 1595 FL patients.
  • Mean monthly costs per patient were US$11,890 for DLBCL and US$10,460 for FL.
  • Healthcare costs and utilization, including chemotherapy, inpatient admissions, and outpatient services, decreased from year 1 to year 2 post-diagnosis.

Conclusions:

  • The economic burden of treated DLBCL and FL is substantial.
  • The highest costs and utilization are observed in the first year after diagnosis.
Abstract

Keywords:
costdiffuse large B-cell lymphomaeconomic burdenfollicular lymphomahealthcare utilizationreal-worldretrospectivetreatment

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