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Updated: Feb 8, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
[When and how to investigate myocardial viability in clinical practice]
Elena Giulia Milano1, Tobias Andreas Fuchs2, Alice Niero3
1Bristol Heart Institute, Bristol NIHR Biomedical Research Centre, University Hospitals Bristol and University of Bristol, Bristol, UK - Divisione di Cardiologia, Dipartimento di Medicina, Università degli Studi, Verona.
Insights
Assessing myocardial viability is key for patients with coronary artery disease and left ventricular dysfunction. Identifying viable myocardium can guide revascularization decisions, potentially improving heart function and patient outcomes.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Assessing myocardial viability is crucial for patients with coronary artery disease (CAD) and left ventricular (LV) systolic dysfunction.
- Identifying viable myocardium guides treatment decisions, potentially improving LV function and patient outcomes.
Purpose of the Study:
- To review the role of noninvasive imaging in assessing myocardial viability.
- To highlight the different definitions and information provided by various imaging modalities.
Main Methods:
- Review of current noninvasive imaging techniques for myocardial viability assessment.
- Comparison of cardiac magnetic resonance, stress echocardiography, and nuclear imaging.
Main Results:
- Different imaging modalities define myocardial viability differently.
- Each technique offers unique information valuable for clinical decision-making.
Conclusions:
- Noninvasive imaging is essential for evaluating myocardial viability in patients with CAD and LV dysfunction.
- Understanding modality-specific definitions of viability is important for cardiologists to optimize patient care.
Abstract:
The assessment of myocardial viability is a crucial step in the work-up of patients with coronary artery disease and left ventricular (LV) systolic dysfunction. Myocardial revascularization should be considered in patients with viable myocardium and LV systolic dysfunction, since this could improve LV function and outcomes.Noninvasive imaging plays a key role in the study of viability and different modalities are currently available, including cardiac magnetic resonance, stress echocardiography and nuclear imaging. The definition of myocardial viability is different, depending on the imaging technique used and it is important for cardiologists to know the information that each modality can offer in this setting.
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