Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Review and Preview01:10

Review and Preview

8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

11.5K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.5K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

998
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
998
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.5K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.5K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

639
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
639
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.7K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TRPS1 and GATA3 expression in BRG1/SMARCA4-deficient malignant neoplasms.

Human pathology·2026
Same author

Limited predictive value of PD-L1 TPS for pathological response in NSCLC is not attributable to interobserver variability.

Lung cancer (Amsterdam, Netherlands)·2026
Same author

Thymic hyperplasia with lymphoepithelial sialadenitis-like features A single-institution series of 21 new cases.

Human pathology·2026
Same author

Machine Learning Assessment of Pathologic Response in Lung Cancer Resections After Neoadjuvant Therapy-IASLC MPR Project.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026
Same author

Solid, cystic, and mucinous spindle cell thymomas (WHO type A): A clinicopathological and immunohistochemical study of 7 cases.

Human pathology·2026
Same author

From the archives of MD Anderson Cancer Center: Paraneoplastic autoimmune multiorgan syndrome (PAMS) associated with stroma-rich Castleman disease.

Annals of diagnostic pathology·2026

Related Experiment Video

Updated: Feb 8, 2026

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
08:17

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

Published on: February 20, 2017

15.0K

Pulmonary Sarcomatoid Carcinomas: A Review.

Annikka Weissferdt1

  • 1Department of Pathology, MD Anderson Cancer Center, Houston, TX.

Advances in Anatomic Pathology
|June 19, 2018
PubMed
Summary

Pulmonary sarcomatoid carcinomas are poorly understood rare lung tumors. Recent research suggests they are dedifferentiated non-small cell lung cancers, necessitating updated classification and management strategies.

Area of Science:

  • Pulmonary pathology
  • Oncology
  • Cancer biology

Background:

  • Pulmonary sarcomatoid carcinomas (PSCs) are rare bronchopulmonary neoplasms.
  • Defined by a sarcomatoid component (spindle or giant cells), leading to a heterogeneous classification.
  • Current diagnosis relies solely on light microscopy, lacking ancillary testing.

Purpose of the Study:

  • To review current understanding of PSCs.
  • To explore emerging immunohistochemical and molecular data.
  • To discuss future directions in classification and patient management.

Main Methods:

  • Literature review of recent advances in PSC research.
  • Analysis of immunohistochemical and molecular findings.
  • Synthesis of data to inform classification and management.

More Related Videos

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

855
Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
10:03

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension

Published on: June 27, 2025

801

Related Experiment Videos

Last Updated: Feb 8, 2026

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
08:17

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

Published on: February 20, 2017

15.0K
Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

855
Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
10:03

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension

Published on: June 27, 2025

801

Main Results:

  • PSCs are increasingly recognized as poorly differentiated or dedifferentiated variants of conventional non-small cell lung carcinomas.
  • These tumors share similar immunophenotypic and molecular signatures with conventional non-small cell lung carcinomas.
  • Heterogeneity in clinical, morphologic, and prognostic features exists within PSCs.

Conclusions:

  • Pulmonary sarcomatoid carcinomas represent a spectrum of dedifferentiated lung cancers.
  • Immunohistochemical and molecular methods are crucial for accurate classification.
  • Revised diagnostic criteria and management strategies are needed for these rare tumors.