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Related Concept Videos

Termination of Translation01:44

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The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
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Cleaning, Sterilization, and Disinfection01:30

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Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
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In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
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As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
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An interesting force in everyday life is the force of drag on an object when it is moving in a fluid. Like friction, the drag force always opposes the motion of an object. Unlike simple friction, the drag force is proportional to some function of the velocity of the object in that fluid. This functionality is complicated and depends upon the shape of the object, its size, its velocity, and the fluid it is in. For most large objects, such as cyclists, cars, and baseballs, that are not moving too...
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A Paradigm Shift Toward Terminally Sterilized Devices.

Aakash Agarwal1,2, Adam MacMillan2, Vijay Goel1,2

  • 1Department of Bioengineering and Orthopaedic Surgery, Engineering Center for Orthopaedic, Research Excellence (E-CORE), University of Toledo.

Clinical Spine Surgery
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Summary
This summary is machine-generated.

Terminally sterilized medical devices offer a simpler solution to reprocessing challenges. They reduce logistical burdens, costs, and risks associated with traditional sterilization methods.

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Area of Science:

  • Medical Device Reprocessing
  • Sterilization Technologies
  • Healthcare Logistics

Background:

  • Conventional reprocessing of medical devices presents significant logistical, financial, and safety challenges.
  • Issues include complex staffing, high operational costs, delays, and potential adverse events like surgical-site infections.
  • Liability concerns arise from the unquantifiable nature of reprocessing and the introduction of new technologies.

Purpose of the Study:

  • To evaluate the logistical, cost, and adverse effect implications of current sterile processing department practices.
  • To assess how terminally sterilized devices can mitigate the challenges associated with conventional reprocessing.

Main Methods:

  • This review synthesizes information on the complexities and risks of medical device sterilization.
  • It contrasts the characteristics of conventional reprocessing with terminally sterilized single-use devices.
  • An evaluation of associated costs, logistics, and potential adverse effects is presented.

Main Results:

  • Reprocessing medical devices involves demanding logistics, operational costs, and liability risks.
  • Terminally sterilized single-use devices eliminate these reprocessing-related complexities.
  • The shift to terminal sterilization offers a streamlined approach to device management.

Conclusions:

  • Terminally sterilized devices present a simpler and safer alternative to traditional reprocessing.
  • Adopting terminally sterilized devices can circumvent the logistical and cost burdens of sterile processing departments.
  • This approach enhances patient safety and operational efficiency in healthcare settings.