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LC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study

Bertrand Rochat1, Rayane Mohamed2, Pierre-Edouard Sottas3

  • 1Protein Analysis Facility, Center for Integrative Genomics (CIG), University of Lausanne, CH-1015 Lausanne, Switzerland. bertrand.rochat@chuv.ch.

Metabolites
|June 20, 2018
PubMed
Summary

Untargeted diagnostic screening (UDS) using high-resolution mass spectrometry (HRMS) can identify unexpected compounds in patient samples. This metabolome analysis method shows promise for preliminary diagnosis when standard methods fail.

Keywords:
clinical/biomedical analysisdiagnosticforensic/toxicologyhigh resolution mass spectrometryliquid chromatographymetabolomicsscreeninguntargeted

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