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Modeling Bacteria-Phage Interactions and Its Implications for Phage Therapy
Saptarshi Sinha1, Rajdeep K Grewal1, Soumen Roy1
1Bose Institute, Kolkata, India.
Abstract:
Bacteriophages are more abundant than any other organism on our planet. The interaction of bacteriophages and bacteria and their coevolution is well known. In this chapter, we describe various aspects of modeling such systems and their dynamics. We explore their interaction in: (i) liquid media, which leads to well-mixed populations and (ii) solid media, where their interaction is spatially restricted. Such modeling, when used in conjunction with experiments would not only shed deep insight into the underlying dynamics but also provide useful clues toward potential therapeutic applications.
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