Chart for renal tumor microwave ablation from human study

Area of Science:

• Urology
• Oncology
• Radiology

Background:

• Renal tumors often require minimally invasive treatments.
• Microwave ablation (MWA) is an effective thermal ablation technique for renal cell carcinoma.
• Standardized MWA charts are crucial for predictable treatment outcomes.

Purpose of the Study:

• To establish precise microwave ablation (MWA) charts for human renal tumors based on varying time and power settings.
• To compare the generated MWA charts with those provided by the HS AMICA manufacturer.

Main Methods:

• 54 patients with renal cancers underwent MWA using the HS AMICA system.
• Ablation zone dimensions were measured via CT scans one month post-procedure.
• Dimensions were correlated with MWA power (40W or 60W) and exposure time (5, 10, 15 min).

Main Results:

• Ablation volume increased linearly with time at 40W (30% per 5 min).
• At 60W, a significantly greater volume increase (112%) was observed.
• MWA produced larger ablation zones than manufacturer charts, particularly in antero-posterior diameter (P<0.05).

Conclusions:

• MWA with the AMICA generator yields reproducible ablation areas for specific time and power settings in renal tumors.
• The developed MWA charts are recommended over manufacturer data, which is based on porcine liver and shows significant discrepancies.