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Comparing the effects of shallomin lotion and cryotherapy on treating plane warts

Reza Yaaghubi1, Mohammad Hassan Pipelzade2, Mansur Amin3

  • 1Department of Dermatology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Journal of Family Medicine and Primary Care
|June 20, 2018
PubMed
Abstract

Insights

Shallomin extract, despite its antimicrobial properties, was not effective in reducing the size or number of plane warts compared to cryotherapy. This study suggests shallomin is not a clinically viable treatment for plane warts.

Area of Science:

  • Dermatology
  • Phytotherapy
  • Viral Infections

Background:

  • Warts are common, transmissible skin infections caused by the human papillomavirus.
  • Treatment selection for warts depends on patient factors and therapeutic goals.
  • Shallomin (Hirtifolium Boiss extract) possesses antibacterial properties, but its efficacy for warts was unstudied.

Purpose of the Study:

  • To compare the effectiveness of shallomin extract with cryotherapy for treating plane warts.
  • To evaluate shallomin's potential as a therapeutic agent for viral skin lesions.

Main Methods:

  • A randomized clinical trial involving 40 patients with plane warts.
  • Patients were allocated to two groups (A and B) using block randomization.
  • Data were analyzed using descriptive statistics and inferential tests (Chi-square, Fisher's exact, t-test) with SPSS v16.0.

Main Results:

  • Shallomin treatment did not result in a statistically significant reduction in wart size or number.
  • Cryotherapy demonstrated a greater effect in reducing wart burden compared to shallomin.

Conclusions:

  • Shallomin extract, despite reported antibacterial, antifungal, and anti-herpetic properties, is not clinically effective for treating plane warts.
  • This study represents the first investigation into shallomin's efficacy for plane warts, indicating it is not a suitable therapeutic option.
Keywords:
Cryotherapydermatologyshallomin lotion

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