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Updated: Feb 8, 2026

Pulling Membrane Nanotubes from Giant Unilamellar Vesicles
Published on: December 7, 2017
Membrane Trafficking: A Little Flexibility Helps Vesicles Get into Shape
1Institut Jacques Monod, UMR7592 CNRS Université Paris-Diderot, Sorbonne Paris Cité, Paris, France.
Abstract:
Formation of a transport vesicle in membrane trafficking pathways requires deformation of the membrane to form a highly curved structure. A recent study reveals a crucial function for the conical lipid lysophosphatidylinositol in reducing the bending rigidity of the membrane during COPII vesicle budding in the early secretory pathway.
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