The Novel PrisMax Continuous Renal Replacement Therapy System in a Multinational, Multicentre Pilot Setting

Area of Science:

• Nephrology
• Intensive Care Medicine
• Biomedical Engineering

Background:

• Continuous renal replacement therapy (CRRT) is crucial for critically ill patients.
• The PrisMax system represents a novel advancement in CRRT technology.
• Comparison with the previous Prismaflex system is essential for evaluating performance.

Purpose of the Study:

• To prospectively evaluate the performance of the novel PrisMax CRRT system.
• To compare the PrisMax system against its predecessor, the Prismaflex.
• To assess user satisfaction with the PrisMax system.

Main Methods:

• Prospective data collection from 7 ICUs in 6 countries.
• Analysis of PrisMax device data logs, including treatment time, filter life, downtime, delivered dose, and alarms.
• User satisfaction survey conducted at 3 participating ICUs.

Main Results:

• Significantly improved filter life span and reduced downtime compared to Prismaflex.
• Fewer blood pump stops and malfunction alarms with the PrisMax system.
• High user satisfaction scores regarding ease of use and friendliness.

Conclusions:

• The PrisMax CRRT device demonstrates safety and superior performance over the Prismaflex.
• The system offers significant improvements in key treatment parameters.
• User feedback supports the PrisMax system's efficacy and usability.