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Updated: Feb 8, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Antiplatelet and anticoagulation therapy during percutaneous coronary interventions: A review for the
Craig Basman1, Afnan Tariq1, Yuvrajsinh J Parmar1
1Department of Cardiovascular Medicine, Lenox Hill Hospital-Northwell Health, New York, New York.
Abstract:
Pharmacotherapy for percutaneous coronary interventions is essential to optimize the balance between thrombosis and bleeding. Currently, choices abound for the selection of antiplatelet and anticoagulation therapies during percutaneous intervention (PCI). This review article discusses the mechanisms, pharmacokinetics/dynamics, and clinical data behind the various pharmacotherapies including; aspirin, thienopyridines, glycoprotein IIb/IIIa inhibitors, vorapaxar, heparin, direct thrombin inhibitors, and factor Xa inhibitors.
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