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Updated: Feb 8, 2026

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
Published on: February 25, 2022
Fundamental ingredients for discontinuous phase transitions in the inertial majority vote model
Jesus M Encinas1, Pedro E Harunari1, M M de Oliveira2
1Instituto de Física, Universidade de São Paulo, Caixa Postal 66318 05315-970, São Paulo, São Paulo, Brazil.
Abstract:
Discontinuous transitions have received considerable interest due to the uncovering that many phenomena such as catastrophic changes, epidemic outbreaks and synchronization present a behavior signed by abrupt (macroscopic) changes (instead of smooth ones) as a tuning parameter is changed. However, in different cases there are still scarce microscopic models reproducing such above trademarks. With these ideas in mind, we investigate the key ingredients underpinning the discontinuous transition in one of the simplest systems with up-down Z2 symmetry recently ascertained in [Phys. Rev. E 95, 042304 (2017)]. Such system, in the presence of an extra ingredient-the inertia- has its continuous transition being switched to a discontinuous one in complex networks. We scrutinize the role of three central ingredients: inertia, system degree, and the lattice topology. Our analysis has been carried out for regular lattices and random regular networks with different node degrees (interacting neighborhood) through mean-field theory (MFT) treatment and numerical simulations. Our findings reveal that not only the inertia but also the connectivity constitute essential elements for shifting the phase transition. Astoundingly, they also manifest in low-dimensional regular topologies, exposing a scaling behavior entirely different than those from the complex networks case. Therefore, our findings put on firmer bases the essential issues for the manifestation of discontinuous transitions in such relevant class of systems with Z2 symmetry.
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