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Burden of heart failure on patients from China: results from a cross-sectional survey
James Ds Jackson1, Sarah E Cotton1, Sara Bruce Wirta2
1Real World Research, Adelphi Real World, Bollington, UK.
Insights
Chronic heart failure (HF) significantly disrupts daily life for Chinese patients, impacting work, quality of life, and incurring costs. New therapies are crucial to alleviate this burden.
Area of Science:
- Cardiology
- Public Health
- Health Economics
Background:
- Limited data exists on the specific burden of chronic heart failure (HF) in China.
- Understanding this burden is critical for developing targeted interventions.
Purpose of the Study:
- To describe the multifaceted burden of heart failure (HF) on patients in China.
- To quantify the impact of HF on daily life, work, and quality of life.
Main Methods:
- A cross-sectional survey involving 150 cardiologists and 933 heart failure (HF) patients in China.
- Data collected via patient record forms and patient questionnaires.
- Utilized EuroQol questionnaire and visual analog scale for quality of life assessment.
Main Results:
- Heart failure (HF) patients reported significant disruption to daily life (median score 4/10).
- Employed patients experienced substantial work absence (10%) and impairment (29%) due to HF.
- Health-related quality of life (QoL) was negatively impacted, with associated treatment and caregiving costs.
Conclusions:
- Heart failure (HF) imposes a considerable burden on Chinese patients, affecting daily activities and QoL.
- There is a pressing need for novel and improved therapies to mitigate the impact of HF.
- Addressing the HF burden is essential for both patients and the healthcare system.
Purpose:
Little evidence exists on the burden that chronic heart failure (HF) poses specifically to patients in China. The objective of this study, therefore, was to describe the burden of HF on patients in China.
Materials And Methods:
A cross-sectional survey of cardiologists and their patients with HF was conducted. Patient record forms were completed by 150 cardiologists for 10 consecutive patients. Patients for whom a patient record form was completed were invited to complete a patient questionnaire.
Results:
Most of the 933 patients (mean [SD] age 65.8 [10.2] years; 55% male; 80% retired) included in the study received care in tier 2 and 3 hospitals in large cities. Patients gave a median score of 4 on a scale from 1 (no disruption) to 10 (severe disruption) to describe how much HF disrupts their everyday life. Patients in paid employment (8%) missed 10% of work time and experienced 29% impairment in their ability to work due to HF in the previous week. All aspects of patients' health-related quality of life (QoL) were negatively affected by their condition. Mean ± SD utility calculated by the 3-level 5-dimension EuroQol questionnaire was 0.8±0.2, and patients rated their health at 70.3 (11.5) on a 100 mm visual analog scale. Patients incurred costs associated with HF treatment, travel, and professional caregiving services.
Conclusion:
HF is associated with poor health-related QoL and considerable disruption in patients' lives. Novel and improved therapies are needed to reduce the burden of HF on patients and the health care system.
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