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Biomarkers in early-phase trials: fundamental issues

Laura M Yee1, Tracy G Lively1, Lisa M McShane1

  • 1Division of Cancer Treatment & Diagnosis, National Cancer Institute, National Institutes of Health, Rockville, MD, 20850, USA.

Bioanalysis
|June 21, 2018
PubMed

Keywords:
analytical validationbiomarkersclinical trialsdrug developmentearly-phase trialsbiomarker validationearly-phase clinical trialsclinical trial designfit-for-purpose testing

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