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Magnesium Sulfate-Induced Motor Evoked Potential Changes.

Tucker Johnson1, Emily B Kale1, Aatif M Husain1,2,3

  • 1a Duke University Medical Center , Durham , North Carolina.

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|June 21, 2018
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Summary
This summary is machine-generated.

A magnesium sulfate bolus can temporarily reduce motor evoked potentials (MEPs) during surgery. These neurophysiological signals returned to baseline within 20 minutes, with no new patient deficits observed.

Keywords:
Magnesium sulfatemotor evoked potentialsneurophysiologic intraoperative monitoring

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Area of Science:

  • Neurosurgery
  • Neurophysiology
  • Anesthesiology

Background:

  • Motor evoked potentials (MEPs) are crucial for intraoperative neurophysiological monitoring.
  • Various factors including anesthesia, homeostasis, surgical procedures, and technical issues can alter MEPs.

Purpose of the Study:

  • To report a case where magnesium sulfate administration caused a significant change in MEPs during surgery.
  • To highlight the importance of considering magnesium sulfate as a potential cause for MEP changes.

Main Methods:

  • Intraoperative neurophysiological monitoring using MEPs.
  • Case observation of MEP amplitude changes following magnesium sulfate administration.

Main Results:

  • A bolus of magnesium sulfate led to a loss of MEP amplitude.
  • MEP responses recovered to near baseline levels approximately 20 minutes after administration.
  • The patient experienced no new postoperative neurological deficits.

Conclusions:

  • Magnesium sulfate can reversibly affect MEPs during neurophysiological monitoring.
  • Clinicians should consider magnesium sulfate administration when observing MEP changes during surgery.
  • Prompt recognition and consideration of magnesium sulfate can prevent misinterpretation of MEP data.