Related Experiment Video
Updated: Feb 8, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
[Study on periodic changes in onset of aortic dissection]
1Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Insights
Acute aortic dissection shows distinct onset patterns, occurring more frequently in the afternoon and winter months. These temporal variations highlight potential triggers for this serious cardiovascular event.
Area of Science:
- Cardiovascular Medicine
- Epidemiology
- Medical Statistics
Background:
- Acute aortic dissection (AAD) is a life-threatening condition with significant morbidity and mortality.
- Understanding the temporal patterns of AAD onset may provide insights into its pathophysiology and potential preventive strategies.
Purpose of the Study:
- To investigate the periodic changes and temporal patterns in the onset of acute aortic dissection.
- To analyze onset regularities based on time of day, weekday, month, and season.
Main Methods:
- Retrospective analysis of clinical data from 1,121 patients with AAD treated between 2010 and 2016.
- Statistical analysis of disease onset timing across different diurnal periods, weekdays, months, and seasons.
Main Results:
- The peak onset period for AAD was in the afternoon (13:00-18:00), with lower frequency in the early morning (1:00-6:00).
- Monday showed the highest incidence of AAD onset, while Friday had the lowest.
- January and winter months exhibited a higher frequency of AAD onset compared to July and summer.
- No significant differences in onset patterns were observed across age groups (≥65 vs <65), or in patients with or without hypertension or Marfan syndrome.
Conclusions:
- Acute aortic dissection exhibits significant periodic changes in onset, with a predilection for the afternoon and winter.
- These findings suggest that environmental and physiological factors may influence the timing of AAD events.
- Further research into circadian and seasonal influences could inform proactive management and prevention of aortic dissection.
Abstract:
Objective: To investigate theperiodic changes in onset of aortic dissection. Methods: The clinical data of 1 121 patients with acute aortic dissection from Hebei province, treated at Fuwai hospital from January 1, 2010 to December 31, 2016, were collected and analyzed retrospectively. The regularity for the onset of aortic dissection was analyzed according to daytime (1:00 to 6:00, 7:00 to 12:00, 13:00 to 18:00, and 19:00 to 24:00), weekday, month, and quarter. Meanwhile,the differences in various type of aortic dissection patient were also compared. Results: The patients were (51.4±12.0) years old,77.88% (873 cases)were male and 69.05% (774 cases) were type A aortic dissection.The peak period for the onset of the disease in a day was from 13:00 to 18:00 (401 cases. 35.77%),and disease onset was less frequent from 1:00 to 6:00 (196 cases, 17.48%).The peak weekday of disease onset was Monday (173 cases, 15.43%) , and disease onset was less frequent on Friday (153 cases, 13.65%) . The peak month of disease onset was January (135 cases, 12.04%), and disease onset was less frequent in July(54 cases, 4.82%). The peak season of disease onset was winter (349 cases, 31.13%), and disease onset was less frequent in summer (184 cases, 16.41%). Number of disease onset was similar between ≥65 years old and<65 years old groups, with or without hypertension groups, with or without Marfan syndrome groups at different periods of a day, each weekday, and seasons(all P>0.05). Conclusion: There are periodic changes in the onset of acute aortic dissection,which is higher in winter than in summer, higher in the afternoon than in the morning.
Related Concept Videos
The Periodic Table
Periodic Classification of the Elements
Effective Value of a Periodic Waveform
The effective value of a periodic current represents the direct current (DC) that conveys the same average power to a resistor as the periodic current itself. This concept is crucial when assessing AC circuits. To determine the...
The Periodic Table and Organismal Elements
The Periodic Table and Organismal Elements
Periodic Table Provides Information...
Aortic Regurgitation I: Introduction

