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Published on: December 9, 2020
Expression of Galectins-1 and Galectin-3 in Stomach and Colorectal Cancer with Tissue Eosinophilia
Yu V Kolobovnikova1, A I Dmitrieva2,3, K I Yankovich2,3
1Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. kolobovnikova.julia@mail.ru.
Abstract:
We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was detected only in patients with gastrointestinal cancer associated with eosinophilia. Association of galectin-1 expression with eosinophilic infiltration of the tumor tissue in stomach and colorectal cancer was detected.
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