Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.1K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.1K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.1K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.1K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

2.4K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
2.4K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

968
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
968
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

563
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
563

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Periodontal Diseases and Conditions in Children and Adolescents Associated With Systemic Disorders: A Systematic Review.

Journal of clinical periodontology·2026
Same author

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report.

Journal of clinical periodontology·2026
Same author

Gingival and periodontal diseases and conditions in children and adolescents: consensus report.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2026
Same author

Descriptive Analysis of Periodontitis Case Detection and Selected Comorbidities in Danish Private Dental Practices.

Journal of clinical periodontology·2025
Same author

Dual-excitation multispectral fluorescence lifetime imaging handheld endoscope for label-free metabolic and biochemical imaging of the oral mucosa.

Optics letters·2025
Same author

The peer review process: Growing problem in recruiting qualified reviewers.

Acta odontologica Scandinavica·2025

Related Experiment Video

Updated: Feb 8, 2026

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model
06:02

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on: July 26, 2011

37.4K

Non-plaque-induced gingival diseases.

Palle Holmstrup1, Jacqueline Plemons2, Joerg Meyle3

  • 1Section of Periodontology, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Journal of Clinical Periodontology
|June 22, 2018
PubMed
Summary

Common gingivitis stems from plaque, but rarer non-plaque gingival diseases often indicate underlying systemic issues or localized pathology. A new classification categorizes these diverse gingival conditions by their cause.

Keywords:
classificationdiagnosis oralepulisgingivagingival diseasesimmunologicalinflammationmouth mucosaoral manifestationsoral medicineperiodontal diseaserare diseases

More Related Videos

Isolation, Processing and Analysis of Murine Gingival Cells
09:47

Isolation, Processing and Analysis of Murine Gingival Cells

Published on: July 2, 2013

20.0K
Isolation and Culture of Primary Human Gingival Epithelial Cells using Y-27632
06:47

Isolation and Culture of Primary Human Gingival Epithelial Cells using Y-27632

Published on: November 6, 2021

5.9K

Related Experiment Videos

Last Updated: Feb 8, 2026

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model
06:02

Detection of Neuritic Plaques in Alzheimer's Disease Mouse Model

Published on: July 26, 2011

37.4K
Isolation, Processing and Analysis of Murine Gingival Cells
09:47

Isolation, Processing and Analysis of Murine Gingival Cells

Published on: July 2, 2013

20.0K
Isolation and Culture of Primary Human Gingival Epithelial Cells using Y-27632
06:47

Isolation and Culture of Primary Human Gingival Epithelial Cells using Y-27632

Published on: November 6, 2021

5.9K

Area of Science:

  • Oral pathology
  • Periodontology
  • Dental medicine

Background:

  • Plaque-induced gingivitis is a prevalent human inflammatory condition.
  • Less common non-plaque-induced gingival diseases, while infrequent, can be clinically significant.
  • These lesions may signal systemic health problems or be confined to gingival tissues.

Purpose of the Study:

  • To propose a comprehensive classification system for non-plaque-induced gingival diseases.
  • To categorize gingival lesions based on their underlying etiology.
  • To aid in the diagnosis and understanding of diverse gingival pathologies.

Main Methods:

  • Review and synthesis of existing literature on gingival diseases.
  • Development of a classification framework based on etiological factors.
  • Categorization of lesions into distinct groups.

Main Results:

  • A proposed classification includes eight etiological categories:
  • Genetic/Developmental disorders
  • Specific infections
  • Inflammatory and immune conditions and lesions
  • Reactive processes
  • Neoplasms
  • Endocrine, Nutritional and metabolic diseases
  • Traumatic lesions
  • Gingival pigmentation.

Conclusions:

  • The proposed classification provides a structured approach to understanding non-plaque-induced gingival diseases.
  • Recognizing these diverse etiologies is crucial for accurate diagnosis and patient management.
  • This framework highlights the importance of considering systemic factors in gingival health.