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Updated: Feb 8, 2026

Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method
Published on: December 25, 2016
[Nitric Oxide Signaling Pathway and Vascular Activity]
Abstract:
Nitric oxide-cyclic guanosine 3',5'-monophosphate (cGMP)-cGMP dependent protein kinase signaling pathway is a key mechanism for the modulation of vascular function. The progress in this area of recent years was briefly summarized in this article, in particular, regarding the redox-dependent dimerization of the relevant signaling molecules and their physiological significance as well as the role of soluble guanylyl cyclase-derived cyclic inosine 3',5'-monophosphate as a new messenger for vasoconstriction.
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