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Updated: Feb 8, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Validated registry of pre-dialysis chronic kidney disease: description of a large cohort
Rosalia Maria Nunes Henriques Huaira1, Rogerio Baumgratz de Paula1, Marcus Gomes Bastos1
1Universidade Federal de Juiz de Fora, Núcleo Interdisciplinar de Ensino e Pesquisas em Nefrologia, Juiz de Fora, MG, Brasil.
Insights
Validated electronic health records reveal that elderly, overweight individuals with chronic kidney disease (CKD) require multidisciplinary care. This study highlights the need for improved management of hypertension and diabetes mellitus in CKD patients.
Area of Science:
- Nephrology
- Public Health
- Health Informatics
Background:
- Chronic diseases, including hypertension (SAH) and diabetes mellitus (DM), are leading causes of death in Brazil.
- These conditions are primary drivers of chronic kidney disease (CKD).
Purpose of the Study:
- To validate electronic health record (EHR) data for pre-dialytic CKD patients.
- To characterize the profile of EHR users concerning clinical quality indicators for pre-dialytic CKD.
Main Methods:
- Retrospective cohort study (August 2010 - December 2014).
- Included 1,977 users over 18 with at least two queries.
- Analyzed sociodemographic data, underlying diseases, medications, and clinical control indicators.
Main Results:
- 33.7% of users experienced a decline in glomerular filtration rate.
- Among CKD and DM patients, 36% met initial glycated hemoglobin goals, rising to 52.1% by study end.
- Blood pressure control improved from 34.3% at admission to 49.8% at follow-up.
Conclusions:
- Validated EHR data are crucial for health managers monitoring CKD patients.
- The study population was predominantly elderly and obese, necessitating multidisciplinary care.
- Interventions should focus on slowing disease progression and reducing morbidity and mortality in CKD.
Introduction:
Chronic diseases account for the majority of deaths in Brazil. These include hypertension (SAH) and diabetes mellitus (DM), which are the main causes of chronic kidney disease (CKD).
Objective:
This study aimed to validate the data of an electronic health record and to point out characteristics of the profile of these users in relation to clinical quality indicators for a pre-dialytic CKD.
Methods:
Retrospective cohort, August/2010 to December/2014. Included users > 18 years, with at least two queries. Variables analyzed: sociodemographic, underlying disease, main medications and main clinical indicators of control. A descriptive analysis was performed and the percentage of users was evaluated in the goals at admission and at the end of the study.
Results:
Exported, converted and validated data of 1,977 users with average follow-up time of 21 months. Of these, 51.4% were men, 58% were > 64 years of age and 81.6% were overweight. The main medications in use were diuretics (82.9%), BRAT (62%), Statin (60.7%) and ACE inhibitors (49.9%). The percentage of users with a decline in the glomerular filtration rate was 33.7%. Regarding glycated hemoglobin, users with CKD and DM, 36% were within the initial goal and 52.1% of the final. Blood pressure was at the target for admission at 34.3% and 49.8% at the end of follow-up.
Conclusion:
Validated data are of vital importance for health managers to monitor users. The population of this study is predominantly elderly, obese, requiring multi-professional care to slow the progression of the disease and decrease morbidity and mortality.
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