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Spacer devices for inhaled therapy: why use them, and how?
Walter Vincken1, Mark L Levy2, Jane Scullion3
1Respiratory Division, University Hospital Brussels (UZ Brussel), Vrije Universiteit Brussel, Brussels, Belgium.
ERJ Open Research
|June 22, 2018
Summary
This review covers the use of valved holding chambers (VHCs) with metered-dose inhalers for inhaled therapy. It discusses device properties, risks, benefits, and provides practical usage recommendations for patients and professionals.
Area of Science:
- Pulmonary Medicine
- Pharmaceutical Technology
Background:
- Metered-dose inhalers (MDIs) are common for inhaled therapy.
- Effective delivery of inhaled medications can be challenging.
- Spacers and valved holding chambers (VHCs) are adjuncts to improve MDI use.
Purpose of the Study:
- To review the rationale for using VHCs with MDIs.
- To discuss device variability, risks, and benefits of VHCs.
- To provide practical guidance on VHC usage and maintenance.
Main Methods:
- Extensive literature review.
- Analysis of device physical characteristics and materials.
- Evaluation of evidence for VHC contribution to therapy delivery.
Main Results:
- VHCs offer a rationale for improved inhaled therapy delivery.
- Device properties and ancillary components (e.g., valves) impact performance.
- Evidence supports the tangible contribution of VHCs to therapy.
Conclusions:
- VHCs are valuable tools for optimizing MDI therapy.
- Understanding device variations and proper use is crucial.
- Practical recommendations are provided for correct usage and maintenance.
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