Maternal weight and infections in early childhood: a cohort study

Samuel Videholm1,2, Sven-Arne Silfverdal1, Georges Reniers3,4

  • 1Department of Clinical Sciences, Paediatrics, Umeå University, Umeå, Sweden.

Insights

Maternal overweight and obesity during pregnancy increase the risk of hospitalizations for infectious diseases in early childhood. This includes a notable association with perinatal infections, highlighting the importance of maternal health for infant well-being.

Area of Science:

  • Public Health
  • Epidemiology
  • Pediatrics

Background:

  • Maternal pre-pregnancy weight is a significant factor influencing pregnancy outcomes and infant health.
  • Understanding the link between maternal weight and childhood infectious diseases is crucial for preventative strategies.

Purpose of the Study:

  • To investigate the association between maternal weight status during pregnancy and the incidence of infectious disease hospitalizations in early childhood.
  • To explore specific categories of infectious diseases linked to maternal weight.

Main Methods:

  • A population-based cohort study utilizing national Swedish registers.
  • Inclusion of over 693,000 children born between 1998 and 2006.
  • Analysis of hospitalizations for various infectious diseases within the first five years of life.

Main Results:

  • Overweight and obesity in pregnancy were associated with a higher overall incidence of infectious disease hospitalizations (IRR 1.05 and 1.18, respectively).
  • A strong association was observed between maternal overweight/obesity and perinatal infections (IRR 1.34 and 1.72, respectively).
  • No significant association was found for skin, soft tissue, neurological, digestive, or bloodstream infections.

Conclusions:

  • Maternal overweight and obesity during pregnancy are linked to an increased risk of infectious disease hospitalizations in early childhood.
  • The findings underscore the importance of managing maternal weight for preventing childhood infections, particularly perinatal ones.
Abstract

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