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Influenza B-related meningoencephalitis in adults
Chen Han Yong1,2, Wilson Vallat1, Graham Norton1
1Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia.
Abstract:
We present a case involving an 85-year-old man with acute confusion and new onset seizure following a 1-week history of respiratory prodrome. This case report describes a case of influenza B-related meningoencephalitis supported by evidence of an influenza B infection and temporal relation of the neurological event and respiratory illness in the absence of other identifiable cause. Diagnosis is guided by cerebrospinal fluid profile and nasopharyngeal PCR. Treatment is largely supportive and the effect of vaccination on prevention of this neurological complication remains unclear.
Insights
This case report details an elderly man with influenza B who developed meningoencephalitis, a brain inflammation. Early diagnosis via PCR and CSF analysis is crucial for supportive care in this rare neurological complication.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Influenza B virus is a common respiratory pathogen.
- Neurological complications of influenza, while rare, can be severe.
- Meningoencephalitis presents a significant diagnostic and therapeutic challenge.
Observation:
- An 85-year-old male presented with acute confusion and new-onset seizure.
- Symptoms followed a one-week history of respiratory prodrome.
- Cerebrospinal fluid (CSF) analysis and nasopharyngeal PCR confirmed Influenza B infection.
Findings:
- The patient was diagnosed with influenza B-related meningoencephalitis.
- Neurological symptoms were temporally linked to the respiratory illness.
- No other causative agent for the meningoencephalitis was identified.
Implications:
- This case highlights the potential for severe neurological sequelae from Influenza B.
- Diagnostic confirmation relies on CSF profiling and PCR testing.
- Further research is needed to clarify the role of vaccination in preventing such neurological complications.
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