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Updated: Feb 8, 2026

Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling
Published on: June 9, 2023
Persistent below-knee great saphenous vein reflux after above-knee endovenous laser ablation with 1470-nm laser: a
Walter Junior Boim de Araujo1, Jorge Rufino Ribas Timi1, Carlos Seme Nejm1
1Universidade Federal do Paraná - UFPR, Departamento de Cirurgia, Curitiba, PR, Brazil.
Background:
In endovenous laser ablation (EVLA), the great saphenous vein (GSV) is usually ablated from the knee to the groin, with no treatment of the below-knee segment regardless of its reflux status. However, persistent below-knee GSV reflux appears to be responsible for residual varicosities and symptoms of venous disease.
Objectives:
To evaluate clinical and duplex ultrasound (DUS) outcomes of the below-knee segment of the GSV after above-knee EVLA associated with conventional surgical treatment of varicosities and incompetent perforating veins.
Methods:
Thirty-six patients (59 GSVs) were distributed into 2 groups, a control group (26 GSVs with normal below-knee flow on DUS) and a test group (33 GSVs with below-knee reflux). Above-knee EVLA was performed with a 1470-nm bare-fiber diode laser and supplemented with phlebectomies of varicose tributaries and insufficient perforating-communicating veins through mini-incisions. Follow-up DUS, clinical evaluation using the venous clinical severity score (VCSS), and evaluation of complications were performed at 3-5 days after the procedure and at 1, 6, and 12 months.
Results:
Mean patient age was 45 years, and 31 patients were women (86.12%). VCSS improved in both groups. Most patients in the test group exhibited normalization of reflux, with normal flow at the beginning of follow-up (88.33% of GSVs at 3-5 days and 70% at 1 month). However, in many of these patients reflux eventually returned (56.67% of GSVs at 6 months and 70% at 1 year).
Conclusions:
These data suggest that reflux in the below-knee segment of the GSV was not influenced by the treatment performed.
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