Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammation

Inflammation

Allergic Reactions

Allergic Reactions

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

In the era of AI, omics and organoids, animal models are still needed in cardiovascular research.

Nature reviews. Cardiology·2026

Same author

Antithrombotic therapy for secondary prevention in patients with acute coronary syndromes treated with percutaneous coronary intervention: options for personalization to reduce bleeding or ischaemic risks. A Clinical Consensus Statement of the ESC Working Group on Thrombosis, the Association for Acute CardioVascular Care of the ESC, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the ESC Working Group on Cardiovascular Pharmacology A Clinical Consensus Statement of the ESC Working Group on Thrombosis, the Association for Acute CardioVascular Care of the ESC, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the ESC Working Group on Cardiovascular Pharmacology.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·2026

Same author

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia-Reperfusion Injury and Atherosclerosis Development.

Phytotherapy research : PTR·2026

Same author

Pathophysiology, prevention, and management of coronary microvascular obstruction.

European heart journal·2026

Same author

Subcutaneous Adipose Tissue as a Metabolic Mirror: Transcriptomic Insights Into Glycaemic Dysregulation.

European journal of clinical investigation·2026

Same author

Primed for metabolic syndrome: evidence of cardiac mitochondrial dysfunction preceding disease.

American journal of physiology. Heart and circulatory physiology·2026

Search research articles

Related Experiment Video

Updated: Feb 8, 2026

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

Published on: December 9, 2021

Phytosterols and Inflammation.

Gemma Vilahur^1,2, Soumaya Ben-Aicha¹, Elisa Diaz-Riera¹

¹Cardiovascular Program ICCC, Research Institute - Hospital Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain.

Current Medicinal Chemistry

|June 23, 2018

Summary

Plant sterols and stanols show promise beyond lowering LDL cholesterol, impacting inflammation and oxidative stress for cardiovascular disease prevention. However, clinical evidence for these non-lipid benefits remains inconsistent, requiring further research.

Keywords:

CRP LDL Phytosterols cholesterol cytokines inflammation oxidative stress.

More Related Videos

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

Published on: August 16, 2013

Related Experiment Videos

Last Updated: Feb 8, 2026

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

A Microphysiological System to Study Leukocyte-Endothelial Cell Interaction during Inflammation

Published on: December 9, 2021

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures

Published on: November 22, 2024

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

In vivo Imaging Method to Distinguish Acute and Chronic Inflammation

Published on: August 16, 2013

Area of Science:

Nutrition Science
Cardiovascular Health
Molecular Biology

Background:

Plant sterols/stanols are known to reduce LDL cholesterol.
Emerging evidence suggests benefits for non-lipid cardiovascular risk factors.

Purpose of the Study:

To review current knowledge on the anti-inflammatory effects of plant sterols/stanols.
To assess their relevance in atheroprotection and cardiovascular disease prevention.

Main Methods:

Review of experimental studies (in vitro, animal models).
Analysis of human clinical data on phytosterols and inflammatory markers.

Main Results:

Anti-inflammatory effects demonstrated in experimental models.
Clinical data on inflammatory markers (CRP, cytokines) are inconsistent.
Limited data exists on phytosterols as adjuncts to statin therapy.

Conclusions:

Plant sterols/stanols show potential for cardiovascular disease prevention beyond lipid-lowering.
More clinical research is needed to confirm anti-inflammatory benefits and efficacy in cardiovascular disease prevention.