Related Experiment Video
Updated: Feb 8, 2026
08:16
Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
Published on: February 11, 2019
22.2K
INTRA-OPERATIVE NEED FOR GLUCOSE IN NEWBORNS
Anesteziologiia I Reanimatologiia
|June 23, 2018
Summary
Intraoperative fluid therapy in neonates requires careful glucose administration. Adding glucose to intravenous fluids helps maintain stable blood glucose levels, reducing hypoglycemia during surgery.
Area of Science:
- Neonatal surgery
- Pediatric anesthesiology
- Intensive care medicine
Background:
- Maintaining normal glycemic status is crucial during neonatal surgery.
- Current guidelines lack clarity on intraoperative glucose-containing fluid administration for neonates.
Purpose of the Study:
- To evaluate the impact of intraoperative glucose infusion on glycemic control in newborns undergoing surgery.
- To compare glycemic stability between neonates receiving saline alone versus saline with glucose infusion.
Main Methods:
- A single-center study involving 60 newborns with congenital malformations.
- Patients were divided into two groups: saline infusion only (Group 1) and saline with glucose infusion (2.3 mg/kg/min) (Group 2).
- Blood glucose levels were monitored preoperatively, every 30 minutes intraoperatively, and postoperatively, with corrections as needed.
Main Results:
- Group 1 experienced a high incidence of hypoglycemia (40 episodes in 20 children), particularly during tracheal intubation and skin incision.
- Group 2 showed significantly higher average glucose levels (p=0.03) and a two-fold reduction in hypoglycemia episodes (19 episodes in 12 patients).
- While Group 2 had more stable glucose levels, hyperglycemia was observed more frequently compared to Group 1.
Conclusions:
- Intraoperative blood glucose in neonates is a highly variable parameter.
- Precise glucose dosing in infusion solutions is essential to prevent both hypoglycemia and hyperglycemia in neonates during surgery.
Related Concept Videos
01:02Glucose Homeostasis: Regulation of Blood Glucose
4.3K
Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
4.3K
01:27Glucose Transporters
27.6K
Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
27.6K
01:17Operational Amplifiers
2.0K
The operational amplifier, often referred to as an op-amp, is a multifaceted building block of a circuit. This electronic component functions like a voltage-controlled voltage source and can also be used to create a voltage- or current-controlled current source. The design of an operational amplifier enables it to execute mathematical operations when external components like resistors and capacitors are linked to its terminals. An op-amp has the capacity to sum signals, amplify a signal,...
2.0K
01:27Real Number Operations
339
The concept of real numbers includes all the values that can be represented on a continuous number line. The system began with basic counting values used for enumeration. It later expanded to include values that represent the absence of quantity and opposites of the counting values. When situations required expressing parts of a whole or dividing quantities evenly, values capable of representing such proportions were developed. When written using decimal notation, these values can end or repeat...
339
01:26Glucose Absorption Into the Small Intestine
35.9K
Complex carbohydrates consumed cannot be absorbed into the small intestine in their original form. First, they must be hydrolyzed to a monosaccharide form such as glucose or galactose. These monosaccharides are then transported across the intestinal membrane and into the blood via transcellular transport. The intestinal epithelial cells allow the movement of these monosaccharides with a defined 'entry' through membrane transporter proteins present on their apical membrane and...
35.9K
01:20Vector Operations
2.3K
Vectors are physical quantities that have both magnitude and direction. The vector operations include addition, subtraction, and scalar multiplication.
A vector multiplied by a scalar value is called scalar multiplication. The result obtained is a new vector with a different magnitude. If the scalar is positive, the direction of the vector remains the same, but if it is negative, the direction of the vector is reversed. For example, the product of the mass and velocity yields the momentum.
A vector multiplied by a scalar value is called scalar multiplication. The result obtained is a new vector with a different magnitude. If the scalar is positive, the direction of the vector remains the same, but if it is negative, the direction of the vector is reversed. For example, the product of the mass and velocity yields the momentum.
2.3K