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Updated: Feb 8, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Phenol Neurolysis for the Management of Shoulder Spasticity in Early Recovery From Traumatic Brain Injury: A Case
Manuel F Mas1, Craig DiTommaso2, Sheng Li1
1Department of Physical Medicine and Rehabilitation, University of Texas Health Sciences Center at Houston, Houston, and TIRR Memorial Hermann, Houston, TX.
Insights
Phenol neurolysis effectively treated spasticity and pain in a teenage traumatic brain injury patient. Early intervention with phenol injections led to significant functional recovery and improved limb positioning.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Pain Management
Background:
- Traumatic brain injury (TBI) can lead to secondary complications like spasticity.
- Spasticity and associated pain significantly impair functional recovery after TBI.
- Current management strategies for post-TBI spasticity often require long-term approaches.
Observation:
- A 16-year-old male developed severe spasticity, shoulder girdle dysfunction, and pain post-TBI.
- Phenol (6%) neurolysis was administered to the axillary and radial nerves at 10 weeks post-injury.
- Ultrasound guidance and electrical stimulation were utilized for precise phenol delivery.
Findings:
- Immediate reduction in triceps spasticity and shoulder pain was observed post-phenol injection.
- Gradual improvement in shoulder girdle complex and elbow joint positioning occurred within 2 weeks.
- The patient demonstrated enhanced functional recovery following the intervention.
Implications:
- Early phenol neurolysis may be a viable strategy for managing spasticity in the acute recovery phase after TBI.
- This case highlights the potential for targeted neurolysis to improve functional outcomes and reduce pain.
- Further research is warranted to explore the long-term efficacy and safety of early phenol neurolysis for TBI-related spasticity.
Abstract:
This case describes a 16-year-old boy who suffered a severe traumatic brain injury. The patient gradually recovered but developed debilitating spasticity mainly in left triceps muscle, abnormal positioning of shoulder girdle complex, and shoulder pain. Phenol (6%) was injected to axillary and radial nerves under the guidance of electrical stimulation and ultrasound imaging at 10 weeks after the initial injury. After injection, triceps spasticity and shoulder pain were immediately reduced, and abnormal positions of shoulder girdle complex and elbow joint gradually returned to functional limits over 2 weeks. This case suggests that phenol neurolysis for spasticity management in early recovery could yield functional recovery.Level of Evidence: V.
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