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Seizures with Migraine-like Attacks after Radiation Therapy (SMART): A new meaning of an old acronym
Edoardo Ferlazzo1, Michele Ascoli2, Sara Gasparini2
1Department of Medical and Surgical Sciences, Magna Graecia University, Viale Europa, Catanzaro, Italy; Regional Epilepsy Centre, Great Metropolitan Hospital, Via Melacrino, Reggio Calabria, Italy; Institute of Molecular Bioimaging and Physiology, National Research Council, Viale Europa, Catanzaro, Italy.
Abstract:
Stroke-like migraine attacks after radiation therapy (SMART) is a late-onset complication of cerebral irradiation, clinically characterized by headache, seizures and focal deficits. We describe two patients with SMART presenting with focal status epilepticus and headache. We believe that SMART is a misnomer that misjudge seizures among clinical features and we suggest to rename this entity as " Seizure with Migraine-like Attacks after Radiation Therapy". The new acronym, modified in its meaning but not in its form (SMART), better reflects the main clinical features and may allow neurologists to recognize this condition more easily.
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Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

