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Cross-Sectional Research01:50

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In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
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Profile leveling and cross-sections are surveying methods used to determine and document terrain elevations for infrastructure projects such as highways, railroads, canals, and pipelines. These methods provide data for earthwork planning and alignment of proposed routes.  Profile leveling involves measuring elevations along a fixed line to create a vertical terrain profile. A surveyor sets up a leveling instrument at the benchmark (BM) and records a backsight (BS) to determine the...
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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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Crossing Over01:34

Crossing Over

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Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
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Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Aura in Cluster Headache: A Cross-Sectional Study.

Ilse F de Coo1, Leopoldine A Wilbrink1, Gaby D Ie1

  • 1Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

Headache
|June 23, 2018
PubMed
Summary
This summary is machine-generated.

Cluster headache patients with aura symptoms, often visual, represent 7.0% of cases. These patients show few clinical differences, except for lower alcohol use and more frontal pain, compared to those without aura.

Keywords:
LUCA studyauracluster headacheepidemiologyheadache characteristics

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Area of Science:

  • Neurology
  • Headache Medicine
  • Clinical Neuroscience

Background:

  • Aura symptoms affect up to 23% of cluster headache patients.
  • Clinical characteristics of cluster headache with and without aura are not well understood.

Purpose of the Study:

  • To investigate the prevalence and characteristics of aura in cluster headache.
  • To compare clinical features between cluster headache patients with and without aura.

Main Methods:

  • Validated web-based questionnaires assessed aura and clinical features in 629 cluster headache subjects.
  • Telephone confirmation of International Classification of Headache Disorders, 3rd edition (ICHD-III) aura criteria for positive screeners.

Main Results:

  • Typical aura symptoms, predominantly visual, were reported by 7.0% (44/629) of participants.
  • Participants with aura consumed less alcohol and had a higher prevalence of frontal pain.
  • No other significant clinical differences were observed between groups.

Conclusions:

  • Approximately 7.0% of cluster headache patients experience typical aura, most commonly visual.
  • Aura in cluster headache is not associated with major differences in clinical presentation, apart from alcohol consumption and pain location.