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Updated: Feb 8, 2026

Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
Inverse planning and inverse implanting for breast interstitial brachytherapy. Introducing a new anatomy specific
Efstratios Karagiannis1, Agnes Leczynski1, Nikolaos Tselis2
1Department of Radiation Oncology, German Oncology Center, Limassol, Cyprus.
Abstract:
An innovative template, based on thoracic cage surface reconstructions for breast interstitial brachytherapy was developed. Hybrid-inverse-planning-optimisation-based implantations and brachytherapy plans, using three custom anthropomorphic breast phantoms, were utilised for its validation. A user independent, inverse planning and inverse implanting technique is proposed.
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