Acute Epstein-Barr virus infection and diffuse large-cell lymphoma

The antibody response to Epstein-Barr virus (EBV) has not been fully investigated in previous cases of diffuse large-cell lymphoma associated with infectious mononucleosis. It is not clear, therefore, whether acute EBV infection is related to this malignant condition. In this paper, a case of diffuse large-cell lymphoma accompanied by acute EBV infection is described.