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Updated: Feb 8, 2026
07:05
Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet
Published on: January 3, 2017
9.4K
Toxicity Potential of Nutraceuticals.
Ramesh C Gupta1, Ajay Srivastava2, Rajiv Lall2
1Toxicology Department, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA. rgupta@murraystate.edu.
Methods in Molecular Biology (Clifton, N.J.)
|June 24, 2018
Summary
Nutraceuticals are popular but can pose risks due to contamination and lack of safety data. Pharmacokinetic and interaction studies are crucial for assessing nutraceutical safety and toxicity.
Area of Science:
- Pharmacology
- Toxicology
- Nutritional Science
Background:
- Nutraceutical use has surged in humans and animals due to accessibility and perceived safety.
- However, many nutraceuticals lack comprehensive safety and toxicity data.
- Contamination with toxins like heavy metals and pesticides compromises their safety.
Purpose of the Study:
- To review the toxic potential of nutraceuticals.
- To identify factors influencing nutraceutical safety.
- To highlight the importance of pharmacokinetic and interaction studies.
Main Methods:
- Review of existing literature on nutraceuticals, safety, and toxicity.
- Analysis of factors affecting nutraceutical safety, including contamination and drug interactions.
- Emphasis on pharmacokinetic and toxicokinetic principles.
Main Results:
- Some nutraceuticals possess inherent toxic potential.
- Contamination is a significant safety concern for many products.
- Lack of pharmacological and toxicological data hinders comprehensive safety assessment.
Conclusions:
- Pharmacokinetic/toxicokinetic data are vital for evaluating nutraceutical safety.
- Interaction studies are essential when combining nutraceuticals with therapeutic drugs.
- Further research is needed to establish robust safety profiles for widely used nutraceuticals.
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