Related Experiment Video
Updated: Feb 8, 2026
18:50
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
14.1K
High-frequency wall vibrations in a cerebral patient-specific aneurysm model
Andrea Balasso1,2, Marco Fritzsche3, Dieter Liepsch4
1Department of Earth and Environmental Sciences, Ludwig-Maximilians-Universität, Theresienstr. 41, 80333 Munich, Germany.
Biomedizinische Technik. Biomedical Engineering
|June 24, 2018
Summary
This study measured wall vibrations in a cerebral aneurysm model using laser Doppler vibrometry. Higher elasticity increased vibration amplitude, while flow rate had minimal impact on frequencies.
Area of Science:
- Biomedical Engineering
- Fluid Dynamics
- Medical Imaging
Background:
- High-frequency velocity fluctuations in aneurysms are known from in-vivo and numerical studies.
- In-vitro experimental data on aneurysm wall vibrations are limited, especially using patient-specific models.
Purpose of the Study:
- To investigate wall fluctuations in a patient-specific cerebral fusiform aneurysm model.
- To analyze the influence of wall elasticity and flow rates on vibration characteristics.
Main Methods:
- Used a true-to-scale elastic model of a cerebral fusiform aneurysm derived from patient data.
- Employed laser Doppler vibrometry (LDV) to measure wall vibrations.
- Simulated physiological conditions with a compliant perfusion system, non-Newtonian fluid, and unsteady flow.
Main Results:
- Predominant wall vibration frequencies were observed between 40-60 Hz and 255-265 Hz.
- Increased model elasticity led to higher vibration amplitudes, with stable peak frequencies.
- Flow rate variations showed minimal effect on the frequency domain; embedding the model in fluid enhanced amplitude.
Conclusions:
- Elasticity is a key factor influencing aneurysm wall vibration amplitudes.
- Flow rate has a limited impact on the dominant vibration frequencies in these models.
- LDV is effective for in-vitro analysis of aneurysm wall dynamics under physiological conditions.
Related Concept Videos
01:19Vibrating Concrete
404
Mechanical vibrators are instrumental in compacting newly poured concrete within formwork and around reinforcements. This process is essential to eliminate trapped air pockets and establish a dense concrete mass. One widely used method is vibrating by internal vibrators, often referred to as a poker vibrator or immersion vibrator. It is rapidly inserted through the full depth of the freshly laid concrete and slightly extends into the layer below it (which remains in a plastic state). Consistent...
404
02:43Plant Cell Wall
60.5K
The plant cell wall gives plant cells shape, support, and protection. As a cell matures, its cell wall specializes according to the cell type. For example, the parenchyma cells of leaves possess only a thin, primary cell wall.
60.5K
01:30Aneurysm I: Introduction
437
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
437
01:21Frequency-dependent Selection
24.2K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
24.2K
01:24IR Spectroscopy: Molecular Vibration Overview
4.8K
When Infrared (IR) radiation passes through a covalently bonded molecule, the bonds transition from lower to higher vibrational levels. The fundamental vibrational motions that result in infrared absorption can be classified as stretching or bending vibrations.
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
Stretching vibrations are vibrational motions that occur along the bond line, changing the bond length or distance between two bonded atoms. They are further distinguished as symmetric or asymmetric. In symmetric stretching, the...
4.8K
01:22Aneurysm IV: Nursing Management
481
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
481