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Test Samples for Optimizing STORM Super-Resolution Microscopy
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Thyroid storm after choking.

Ana L Creo1, Bryan C Cannon2, Siobhan T Pittock1

  • 1Division of Pediatric Endocrinology and Metabolism, Mayo Clinic, Rochester, MN, USA.

Journal of Pediatric Endocrinology & Metabolism : JPEM
|June 24, 2018
PubMed
Summary
This summary is machine-generated.

Thyroid storm (TS) is a severe hyperthyroid complication. Promptly treating elevated free thyroxine (FT4) in children is crucial to prevent serious illness and potential mortality.

Keywords:
CT scangraveshyperthyroidismpediatricβ-blocker

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Area of Science:

  • Pediatric Endocrinology
  • Critical Care Medicine
  • Thyroidology

Background:

  • Thyroid storm (TS) is a rare, life-threatening endocrine emergency in patients with hyperthyroidism.
  • Mortality rates for adult TS can be as high as 10%, underscoring its severity.
  • TS is typically precipitated by a trigger event in individuals with pre-existing hyperthyroidism.

Observation:

  • A case of a pediatric patient with untreated hyperthyroidism who developed fulminant TS following a choking episode is presented.
  • Initial symptoms included neck swelling and tachycardia, leading to a misdiagnosis of infection.
  • The patient's condition worsened after a CT scan with iodine contrast, suggesting a potential exacerbation of storm symptoms.

Findings:

  • This case highlights a severe presentation of thyroid storm in an adolescent with previously undiagnosed hyperthyroidism.
  • The administration of iodine contrast during a CT scan may have exacerbated the thyroid storm.
  • A specific treatment strategy and proposed modification for pediatric TS management are discussed.

Implications:

  • Emphasizes the critical importance of recognizing and promptly managing hyperthyroidism in children.
  • Elevated free thyroxine (FT4) levels in pediatric patients necessitate urgent medical evaluation to prevent severe morbidity.
  • Highlights the need for careful consideration of diagnostic procedures, such as contrast-enhanced imaging, in patients with suspected or confirmed thyroid disorders.