Orbital presentation of Rosai-Dorfman disease

To report a case of orbital mass and proptosis, diagnosed as Rosai-Dorfman disease (RDD).

Clinical case report based on the review of clinical charts, radiological images, and histopathology.

A 42-year-old male with orbital mass and proptosis of the right eye. A surgical biopsy was performed, and the diagnosis of RDD was established using microscopy and immunohistochemistry. Definitive management included open tumour cytoreduction, with good response.

The RDD is a rare, benign, proliferative condition of unknown origin. It rarely affects the cranial cavities, with the orbital presentation being very unusual. Diagnostic confirmation is essential for the best surgical management.