Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

890
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
890
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

448
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
448
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

475
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
475
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

642
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
642
Leveling Effect01:29

Leveling Effect

1.4K
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K
High-Level and Low-Level Awareness01:19

High-Level and Low-Level Awareness

784
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
784

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole-Exome Sequencing Identified a Novel Mutation in an Iranian Patient with Epidermolysis Bullosa.

Iranian biomedical journal·2026
Same author

Synchronous Macular Amyloidosis and Brachioradialis Pruritus Successfully Treated With Gabapentin.

Case reports in dermatological medicine·2025
Same author

Maxillary Canine Substitution for a Central Incisor With Severe Root Resorption: A Case Report.

Case reports in dentistry·2025
Same author

Elucidating the Role of Pro-renin Receptors in Pancreatic Ductal Adenocarcinoma Progression: A Novel Therapeutic Target in Cancer Therapy.

Current cancer drug targets·2024
Same author

Targeting Lysyl Oxidase as a Potential Therapeutic Approach to Reducing Fibrotic Scars Post-operatively: Its Biological Role in Post-Surgical Scar Development.

Current drug targets·2023
Same author

Review of the Role of Metabolic Factors in Determining the Post-surgical Adhesion and its Therapeutic Implications, with a Focus on Extracellular Matrix and Oxidative Stress.

Current molecular pharmacology·2023

Related Experiment Video

Updated: Feb 8, 2026

Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
07:55

Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality

Published on: June 2, 2023

1.7K

Serum Zinc Level in Vitiligo: A Case-control Study.

Mina Mirnezami1, Hoda Rahimi2

  • 1Department of Dermatology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.

Indian Journal of Dermatology
|June 26, 2018
PubMed
Summary

Serum zinc levels are significantly lower in generalized vitiligo patients compared to controls. Lower zinc levels correlate with older age and longer disease duration in vitiligo patients.

Keywords:
Melanocytepigmentvitiligozinc

More Related Videos

Toxicity Study of Zinc Oxide Nanoparticles in Cell Culture and in Drosophila melanogaster
06:47

Toxicity Study of Zinc Oxide Nanoparticles in Cell Culture and in Drosophila melanogaster

Published on: September 19, 2019

11.6K
Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
11:24

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains

Published on: March 25, 2015

10.5K

Related Experiment Videos

Last Updated: Feb 8, 2026

Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
07:55

Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality

Published on: June 2, 2023

1.7K
Toxicity Study of Zinc Oxide Nanoparticles in Cell Culture and in Drosophila melanogaster
06:47

Toxicity Study of Zinc Oxide Nanoparticles in Cell Culture and in Drosophila melanogaster

Published on: September 19, 2019

11.6K
Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains
11:24

Direct Protein Delivery to Mammalian Cells Using Cell-permeable Cys2-His2 Zinc-finger Domains

Published on: March 25, 2015

10.5K

Area of Science:

  • Dermatology
  • Immunology
  • Nutritional Science

Background:

  • Vitiligo involves melanocyte destruction, potentially autoimmune, causing depigmentation.
  • Oxidative stress is implicated in vitiligo pathogenesis.
  • Zinc is a vital trace element for melanogenesis and antioxidant defense.

Purpose of the Study:

  • To compare serum zinc levels in vitiligo patients and healthy controls.
  • To investigate the relationship between serum zinc and vitiligo characteristics.

Main Methods:

  • A case-control study involving 103 vitiligo patients and 103 matched controls.
  • Serum zinc levels were quantified using atomic absorption spectrophotometry.

Main Results:

  • Mean serum zinc was 81.3 mcg/dl in generalized vitiligo vs. 91.8 mcg/dl in controls (significant difference).
  • Lower serum zinc levels correlated with longer disease duration.
  • A negative correlation was observed between serum zinc and patient age.

Conclusions:

  • Generalized vitiligo patients exhibit lower serum zinc levels.
  • Serum zinc levels in vitiligo patients are negatively associated with age and disease duration.