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Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
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Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
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Related Experiment Video

Updated: Feb 8, 2026

Derivation of Leptomeninges Explant Cultures from Postmortem Human Brain Donors
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The maxillofacial injuries: A postmortem study.

Raja Rupani1, Mousami Singh1, Vijay Kumar2

  • 1Department of Forensic Medicine and Toxicology, KGMU, Lucknow, Uttar Pradesh, India.

National Journal of Maxillofacial Surgery
|June 26, 2018
PubMed
Summary
This summary is machine-generated.

Maxillofacial fractures are most common in adult males due to road traffic accidents (RTAs). These injuries often involve the maxilla, zygomatic, and mandible, frequently presenting as Le Fort-2 fractures.

Keywords:
Maxillofacial injuriesrailway accidentsroad traffic accidents

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Area of Science:

  • Forensic Medicine
  • Trauma Surgery
  • Anatomy

Background:

  • Maxillofacial fractures are significant injuries with diverse etiologies.
  • Understanding the patterns of these fractures is crucial for forensic analysis and clinical management.
  • Autopsy data provides valuable insights into injury mechanisms and demographics.

Purpose of the Study:

  • To determine the incidence and causes of maxillofacial fractures in autopsy cases at KGMU, Lucknow.
  • To analyze demographic and injury characteristics associated with facial fractures.

Main Methods:

  • A retrospective analysis of 444 autopsy cases with maxillofacial injuries was conducted.
  • Data collected included gender, age, cause of injury, fracture type, and anatomical site.
  • Cases were from the mortuary of KGMU, Lucknow, over a one-year period.

Main Results:

  • Road traffic accidents (RTAs) were the predominant cause of maxillofacial injuries, followed by railway accidents.
  • Maxillofacial fractures were more prevalent in adult males compared to females.
  • Commonly fractured bones included the maxilla, zygomatic, and mandible, with Le Fort-2 fractures being the most frequent type.

Conclusions:

  • Maxillofacial injuries are predominantly observed in adult males, primarily resulting from RTAs.
  • The typical presentation involves fractures of the maxilla, zygomatic, and mandible, often classified as Le Fort-2 fractures.
  • Findings highlight the significant impact of RTAs on facial trauma in the studied population.