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The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Related Experiment Video

Updated: Feb 8, 2026

Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
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Advances in microvascular decompression for hemifacial spasm.

Zhiqiang Cui1, Zhipei Ling1

  • 1Department of Neurosurgery (Functional), Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.

Journal of Otology
|June 26, 2018
PubMed
Summary
This summary is machine-generated.

Microvascular decompression (MVD) effectively treats hemifacial spasm (HFS) by relieving nerve compression. Recent technological advancements aim to enhance MVD efficacy and minimize complications for better patient outcomes.

Keywords:
Hemifacial spasm (HFS)Lateral spread responseMicrovascular decompression (MVD)NeuroendoscopyThree dimensional time of flight magnetic resonance angiography

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Area of Science:

  • Neurosurgery
  • Neurology
  • Medical Technology

Background:

  • Primary hemifacial spasm (HFS) involves involuntary facial muscle contractions caused by neurovascular compression at the facial nerve's root exit zone (REZ).
  • Microvascular decompression (MVD) is a primary surgical treatment for HFS, offering significant efficacy.
  • Despite its effectiveness, MVD carries notable risks of postoperative complications.

Purpose of the Study:

  • To review recent technological advancements relevant to microvascular decompression (MVD) for hemifacial spasm (HFS).
  • To explore how these innovations can improve MVD treatment outcomes.
  • To identify strategies for reducing the incidence of postoperative complications associated with MVD.

Main Methods:

  • Review of recent technological advancements in MVD for HFS.
  • Inclusion of techniques such as lateral spread response (LSR) monitoring, brainstem auditory evoked potentials (BAEPs), 3D time-of-flight magnetic resonance angiography (3D TOF MRA), and intraoperative neuroendoscopy.
  • Analysis of their potential impact on surgical efficacy and complication rates.

Main Results:

  • The reviewed technologies offer potential for enhanced intraoperative assessment and precision during MVD.
  • Advanced neuroimaging and electrophysiological monitoring may aid in identifying offending vessels and protecting neural structures.
  • Intraoperative neuroendoscopy may provide better visualization in challenging anatomical regions.

Conclusions:

  • Technological innovations hold promise for refining MVD procedures for hemifacial spasm.
  • These advancements are crucial for improving treatment efficacy and minimizing the risk of complications.
  • Further research and integration of these technologies can lead to optimized patient care for HFS.