Normative data for TM electrocochleography measures

Area of Science:

• Audiology
• Neurotology
• Diagnostic audiology

Background:

• Ménière's disease (MD) diagnosis relies on clinical symptoms and can be supported by electrophysiological tests.
• Establishing normative data for electrocochleography is crucial for accurate interpretation.

Purpose of the Study:

• To establish normative data for tympanic electrocochleography (TM ECochG) parameters in adults without Ménière's disease (MD).
• To identify TM ECochG variables that differentiate normal ears from those affected by MD.

Main Methods:

• 100 normal-hearing adults (200 ears) without MD symptoms were enrolled.
• Key TM ECochG parameters analyzed included SP/AP amplitude ratio, SP/AP area ratio, and AP latency difference.
• Inclusion criteria ensured subjects had normal hearing, tympanometry, and no MD symptoms.

Main Results:

• No significant differences were found between right and left ears for the measured parameters.
• Normative ranges were established: SP/AP amplitude ratio (0.084-0.356), SP/AP area ratio (0.837-1.671), and AP latency difference (0.0-0.333 ms).

Conclusions:

• Normative TM ECochG data were successfully established for a cohort of healthy adults.
• These established normative values are valuable for distinguishing normal findings from pathological conditions and for monitoring MD patients.