Related Experiment Video
Updated: Feb 8, 2026

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
Published on: June 14, 2016
A Multiple Stimuli-Sensitive Low-Molecular-Weight Gel with an Aggregate-Induced Emission Effect for Sol-Gel
Hao Wang1, Qihong Liu1, Yalong Hu1
1College of Chemistry and Materials Engineering Wenzhou University, Chashan Town 325000 Wenzhou City Zhejiang Province P. R. China.
Abstract:
A low-molecular-weight gel (LMWG) with a hydrazone moiety and an aggregate-induced emission (AIE) unit was fabricated; the self-assembly and disassembly of the LMWG under different stimuli conditions were studied. The LMWG exhibited multiple stimuli sensitivity with temperature, light, ions, and ionic strength. The hydrazone was integrated into the gelator to act as ion sensing sites and hydrogen bond donor groups to fulfil the task of ion recognition of Ni2+, BH4-, and OH-, as well as ion-controlled reversible sol-gel recovery by adding H+ for deprotonation; it also broke under UV irradiation to evoke light-sensitivity. In addition, the sol-gel transition of the gel was detected by the AIE effect. The research provided an effective strategy in fabricating multiple stimuli-sensitive LMWGs for potential biomedical applications.
Related Concept Videos
Two-dimensional Gel Electrophoresis
The first dimension separation uses the isoelectric focusing or IEF technique performed on immobilized pH gradient (IPG) strips that separate proteins according to their isoelectric points.
Biological samples, such...
DNA Agarose Gel Electrophoresis
Gel extraction follows five major steps: running gel electrophoresis to separate fragments, isolating the individual bands, extracting DNA from those bands, and removing the dye and salts from the extracted mixture to obtain pure DNA.
In cloning experiments, both the insert and vector DNA...
Polymers: Defining Molecular Weight
The number average molecular weight (Mn) is the summation of the number...
Polymers: Molecular Weight Distribution
Molecular Spectroscopy: Absorption and Emission
Silica Gel Column Chromatography: Overview
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...

