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A practical guide for the use of indocyanine green and methylene blue in fluorescence-guided abdominal surgery

Labrinus van Manen1, Henricus J M Handgraaf1, Michele Diana2,3,4

  • 1Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

Journal of Surgical Oncology
|June 26, 2018
PubMed

Near-infrared (NIR) fluorescence imaging is gaining clinical acceptance over the last years and has been used for detection of lymph nodes, several tumor types, vital structures and tissue perfusion. This review focuses on NIR fluorescence imaging with indocyanine green and methylene blue for different clinical applications in abdominal surgery with an emphasis on oncology, based on a systematic literature search. Furthermore, practical information on doses, injection times, and intraoperative use are provided.

Keywords:
image-guided surgerynear-infraredoncologyoptical imagingtumor

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