Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Counterfactual Thinking01:19

Counterfactual Thinking

272
Counterfactual thinking is a cognitive process wherein individuals mentally reconstruct alternative versions of past events, often beginning with “what if” or “if only.” This reflective mechanism plays a significant role in shaping emotional experiences and guiding future behavior. Though typically triggered by unfavorable or unexpected outcomes, counterfactual thinking can also emerge in mundane, everyday decisions and experiences, revealing its deep entrenchment in...
272
Critical Thinking I01:24

Critical Thinking I

5.2K
Critical thinking helps decision-making and allows nurses to recognize barriers to success and find solutions to possible issues. It helps to brainstorm and implement ideas to achieve goals. Critical thinking helps acknowledge and state workflow inefficiencies while improving management techniques. Nurses understand the value of critical thinking and look for fellow nurses with critical thinking skills to upgrade their professional standards. Critical thinking can advance a nurse's career...
5.2K
Critical Thinking II01:25

Critical Thinking II

4.7K
Critical thinking is a cognitive process with several attributes. The attributes of critical thinking include the following:
4.7K
Critical Thinking01:19

Critical Thinking

1.2K
Critical thinking involves reflective and productive thinking and the evaluation of evidence. Critical thinkers seek to understand the deeper meaning of ideas, question assumptions, and make independent decisions about what to believe or do. Scientists, for instance, are often critical thinkers. Critical thinking also requires humility about what we know and don't know and the motivation to look beyond the obvious. It is essential for effective problem-solving.
Colleges and universities are...
1.2K
Creative Thinking01:25

Creative Thinking

1.3K
Creative thinking encompasses innovative and unconventional methods for addressing challenges, often leading to groundbreaking solutions. Instead of focusing solely on enhancing existing systems, such as increasing smartphone battery capacity, creative thinking might inspire advancements like energy-efficient batteries or processors that minimize power consumption. This multidimensional approach underscores the importance of exploring novel pathways to innovation.
Divergent thinking is the...
1.3K
Magical Thinking01:29

Magical Thinking

220
Magical thinking encompasses the belief in assumptions that defy logical reasoning yet appear intuitively convincing. It is a common psychological phenomenon that persists across various cultural and individual contexts. While these assumptions contradict empirical evidence and scientific laws, they often serve meaningful psychological roles in promoting emotional resilience and a sense of control, especially under stress or uncertainty.Thought-Action Fusion and the Law of SimilarityA key...
220

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular Detection and Antibiotic Susceptibility Profiling of Mannheimia haemolytica Isolates From Pneumonic Pasteurellosis Suspected Cases of Sheep in Northwestern Ethiopia.

Veterinary medicine and science·2026
Same author

Class A scavenger receptors promote tumor progression and induce a unique macrophage phenotype in a mouse model of spontaneous breast cancer.

Journal of leukocyte biology·2026
Same author

Changes in the public IgM repertoire and its idiotypic connectivity in Alzheimer's disease and frontotemporal dementia.

Journal of neuroimmunology·2025
Same author

When Reassurance Falls Short: Rethinking Vaccine Risk Communication.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2025
Same author

Seroprevalence and risk factors of bluetongue virus infection in sheep and goats in West Gondar zone, Northwest Ethiopia.

Frontiers in veterinary science·2025
Same author

Gamma-irradiated fowl cholera vaccines formulated with different adjuvants induced antibody response and cytokine expression in chickens.

Frontiers in immunology·2025
Same journal

A Novel Anti-Glypican-3 Monoclonal Antibody G<sub>3</sub>Mab-25 for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-mouse ACKR4 Monoclonal Antibodies Developed by N-Terminal Peptide Immunization.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-Mouse C-C Motif Chemokine Receptor 1 Monoclonal Antibodies Developed by the Cell-Based Immunization and Screening Method.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Guidelines for Reporting New Monoclonal Antibodies: Improving Transparency, Reproducibility, and Research Utility.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Establishment of a Novel Anti-EphA4 Monoclonal Antibody, Ea<sub>4</sub>Mab-3, for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Acknowledgment of Reviewers 2025.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
See all related articles

Related Experiment Video

Updated: Feb 8, 2026

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal
06:45

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal

Published on: April 18, 2017

6.6K

Thinking Cancer.

Anastas Pashov1, Cinthia Violeta Hernandez Puente2, Saddam Mohammed Ibrahim2

  • 11 Stephan Angelov Institute of Microbiology , Bulgarian Academy of Sciences, Sofia, Bulgaria .

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
|June 26, 2018
PubMed
Summary
This summary is machine-generated.

Cancer evolves through Darwinian principles of cell survival and variation. Understanding somatic evolution and ecological epigenetics is key to developing effective cancer therapies and overcoming complex tumor-immune interactions.

Keywords:
PDL1anthropomorphicautoantibodiescancerepigenetic ecologymutanome

More Related Videos

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

18.9K
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K

Related Experiment Videos

Last Updated: Feb 8, 2026

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal
06:45

Task Interruption and Resumption Paradigm for Testing the Activation and Pursuit of an Abstract Thinking Goal

Published on: April 18, 2017

6.6K
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

18.9K
Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K

Area of Science:

  • Oncology
  • Evolutionary Biology
  • Genetics

Background:

  • Cancer development is understood through evolutionary theories at multiple levels.
  • Cancer cells exhibit differential survival based on heritable variations, akin to species evolution.
  • Multicellularity controls are disrupted as cancer cells become autonomous.

Purpose of the Study:

  • To highlight the application of evolutionary theories in understanding cancer.
  • To contextualize the use of anthropomorphic terms in describing cancer phenomena.
  • To examine the mechanisms underlying tumor-host interactions, particularly with the immune system.

Main Methods:

  • Conceptual analysis of evolutionary principles applied to cancer.
  • Review of ecological epigenetics in cancer progression.
  • Examination of anthropomorphic language used in cancer research.

Main Results:

  • Cancer progression is viewed as a process of somatic evolution driven by differential cell survival.
  • Ecological epigenetics explains how cells with similar DNA can disrupt tissue homeostasis.
  • Anthropomorphic terms like 'hijacking' are commonly used to describe complex tumor-immune interactions.

Conclusions:

  • Viewing cancer through a Darwinian lens is crucial for therapeutic development.
  • Understanding somatic evolution and epigenetic factors is essential for cancer research.
  • Clarifying the mechanisms behind tumor-immune interactions requires careful consideration of terminology.