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Updated: Feb 8, 2026
10:15
Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin
Published on: November 1, 2019
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Correlations between morphological changes induced by curcumin and its biological activities.
Laura Stoica1, Bogdan Alexandru Stoica, Doiniţa Olinici
1Department of Biochemistry, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania; bogstoica@gmail.com.
Summary
Curcumin, derived from turmeric, shows broad therapeutic potential due to its antioxidant and anti-inflammatory properties. This review highlights curcumin
Area of Science:
- Pharmacology and Molecular Biology
- Cell Biology
- Pathology
Background:
- Curcumin, a polyphenol from turmeric, exhibits diverse biological activities.
- It possesses antioxidant, anti-inflammatory, and anticarcinogenic properties.
- These properties are extensively studied across various therapeutic areas.
Purpose of the Study:
- To review morphological evidence correlating curcumin's biological effects across organ systems.
- To analyze microscopic changes induced by curcumin using various microscopy techniques.
Main Methods:
- Literature review focusing on morphological studies.
- Analysis of studies employing microscopy techniques (e.g., electron microscopy, light microscopy).
Main Results:
- Curcumin demonstrates neuroprotective effects in models of Parkinson's and Alzheimer's disease.
- It shows potential in mitigating cardiovascular pathologies like atherosclerosis.
- Evidence suggests antimetastatic and anticancer activities.
- Curcumin impacts metabolic syndromes, including diabetes, at a morphological level.
Conclusions:
- Curcumin induces significant morphological changes across the central nervous, cardiovascular, and oncological systems.
- Microscopic evidence supports curcumin's broad therapeutic potential.
- Further research into curcumin's mechanisms at the cellular and tissue level is warranted.
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