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Updated: Feb 8, 2026

Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
Morphological features of tongue squamous cell carcinoma diagnosed in Dolj County population between 2012-2014
Petre Costin Mărăşescu1, Adina Andreea Turcu, Veronica Mercuţ
1Department of Prosthetic Dentistry, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania; scrieciu_monica@yahoo.com; Department of Occupational Medicine, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania; ninaionovici@yahoo.com.
Abstract:
Tongue squamous carcinoma can be found in many forms, having a lot of risk factors, and whose morphological characteristics can be used as a prognostic. The purpose of this study was to histologically characterize a number of 54 patients diagnosed between 2012-2014, with tongue squamous carcinoma. Surgical resection specimens of tongue tumors were processed by paraffin inclusion technique. The diagnose samples were reevaluated according to the World Health Organization (WHO) criteria for head and neck tumors diagnosis, by screening the Hematoxylin-Eosin staining sections. The most common histopathological variety of tongue carcinoma observed in our cases was the non-keratinized form, the basaloid and sarcomatoid types of carcinoma being ranked on the last places. The study outlined the prevalence of non-keratinized forms of tongue squamous carcinoma and all types of tumoral invasion patterns have been observed in different percentages.
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