Related Experiment Video

Updated: Feb 8, 2026

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

2.3K

Screening for Latent Tuberculosis Infection in Patients who are Candidate for Biological Therapies in Spain? A

Sarai Quirós1, David de la Rosa2, Ane Uranga3

  • 1Servicio de Neumología, Hospital General Universitario La Paz-Carlos III- Cantoblanco, Madrid, España.

Archivos De Bronconeumologia
|June 27, 2018
PubMed
Abstract

Insights

Adherence to tuberculosis screening guidelines for patients on biological therapies is suboptimal. Improving diagnostic test use and algorithm adherence can further reduce tuberculous disease incidence in this population.

Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Pulmonology

Background:

  • Biological therapies increase tuberculosis risk.
  • Systematic screening for latent tuberculosis infection (LTBI) mitigates this risk.
  • Spanish guidelines for TB prevention in biologic candidates were published in 2016.

Purpose of the Study:

  • To evaluate adherence to 2016 Spanish guidelines for TB prevention in patients receiving biological therapies.
  • Assess the implementation of LTBI screening and chemoprophylaxis.

Main Methods:

  • Multicenter, descriptive, observational study.
  • Anonymous online survey distributed to medical societies involved in biologics.
  • Analysis of 747 responses regarding screening practices and guideline adherence.

Main Results:

  • High screening rates (93.7%) but low appropriate diagnostic test use (36.6%).
  • Moderate chemoprophylaxis recommendation (56.3%) and initiation timing (63.9%).
  • Rheumatology was the most active specialty in screening (54%); pulmonologists advised.

Conclusions:

  • Overall adherence to TB prevention guidelines is poor (56%).
  • Emphasizing correct diagnostic testing and algorithm use is crucial.
  • Further reduction in tuberculous disease incidence is achievable with improved adherence.
Keywords:
Biological therapiesEnfermedad tuberculosaFactor de necrosis tumoral alfaInfección tuberculosa latenteLatent tuberculosis infectionTerapias biológicasTuberculosisTumor necrosis factor-alpha

More Related Videos

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish07:00

Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

Published on: October 8, 2018

11.3K
Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex09:23

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

Published on: June 30, 2019

12.6K

Related Concept Videos

Surveys02:16

Surveys

Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
17.0K
Introduction to Surveying, Plane Surveying and Geodetic Surveys01:27

Introduction to Surveying, Plane Surveying and Geodetic Surveys

Surveying is the art and science of mapping the earth's surface. It involves measuring distances, angles in horizontal or vertical directions, and levels to understand the shape and size of land features. Surveying techniques are essential for various tasks, such as identifying the levels of a land area with reference to a specific point, and mapping undulations and water bodies.There are two main types of surveying: plane surveys and geodetic surveys. Plane surveys assume the earth is flat,...
1.1K
Errors and Mistakes in Surveying01:19

Errors and Mistakes in Surveying

Errors and mistakes in surveying refer to inaccuracies in measurements and data recording. The errors are deviations from the actual value caused by human sensory limitations, equipment flaws, or environmental effects. These errors are typically unintentional and can result from the inherent imperfections in the instruments used, atmospheric conditions, or the observer’s inability to perceive exact measurements. On the other hand, mistakes are caused by the surveyor's lack of...
718
Types of Surveys01:27

Types of Surveys

Surveys are essential for marking property boundaries near water bodies. Different types of surveys are defined, each with its own function. Land surveys mark the property boundaries, while route surveys determine the position of properties on nearby highways. Topographic surveys create maps by capturing the three-dimensional features of the land. Hydrographic surveys focus on the shapes of underwater areas and the movement of streams through the properties. Mine surveys determine the relative...
372
Survey Safety01:28

Survey Safety

Surveying near highways, rough terrain, or power lines involves significant risks. Working along highways is particularly dangerous and requires the use of warning signs and flagmen. It is safest to avoid working directly on roads and use offsets whenever possible. When highway work is unavoidable, it must follow all safety guidelines. Surveyors should wear bright clothing, such as orange reflective vests, to ensure visibility to motorists, coworkers, and hunters. In construction zones, wearing...
413
Data Collection by Survey01:07

Data Collection by Survey

The systematic method of obtaining and analyzing accurate information of a population is called data collection. A survey is a standard method of data collection that involves collecting information from a target human population about their experience, opinion, or knowledge of a product, service, or process. The responses are recorded and interpreted. The most common survey examples are written questionnaires, face-to-face or telephonic conversations, focus groups, and electronic (e-mail or...
9.1K